The transcription elongation factor TCEA3 induces apoptosis in rhabdomyosarcoma
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Homocysteine Induces Heme Oxygenase-1 Expression via Transcription Factor Nrf2 Activation in HepG2 Cells
Background: Elevated level of plasma homocysteine has been related to various diseases. Patients with hyperhomocysteinemia can develop hepatic steatosis and fibrosis. We hypothesized that oxidative stress induced by homocysteine might play an important role in pathogenesis of liver injury. Also, the cellular response designed to combat oxidative stress is primarily controlled by the transcripti...
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Financial support: This work was supported by grants PI071027, PI100104 and RTICC RD06/0020 (to C.M-P, S.R-P, F.A-L and A.C-M) and grant PI080259 (to L.L-T and O.M.T) from the Fondo de Investigaciones Sanitarias-ISCIII from Spain, and AICR grant 08-0621. L.L-T.is funded by the Comissionat per a Universitats i Recerca (CUR) from Departament d'Innovació, Universitats i Empresa (DIUE) de la Genera...
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ژورنال
عنوان ژورنال: Cell Death & Disease
سال: 2020
ISSN: 2041-4889
DOI: 10.1038/s41419-020-2258-x